Tuesday, 28 June 2022

Dermoid vs epidermoid cyst / histopathology, clinical and treatment

Dermoid Cyst

A cyst of the midline of the upper neck of the anterior floor of the mouth of young patients derived from remnants of embryonic skin consisting of a lumen lined by a keratinizing stratified squamous epithelium and containing one or more skin appendages such as hair, sweat, or sebaceous glands.

  • It is an example of cystic teratoma
  • Derived from germinal epithelium entrapped during embryonic development

Clinical features

  • It is present in young adults
  • Present in the upper neck or floor of the mouth
  • Present as painless swelling
  • It has doughy consistency
  • It is 2cm or less in diameter

Histopathological features

  • The lining is orthokeratinized squamous epithelium.
  • Exhibiting a variable number of dermal appendages such as hair follicles sebaceous glands and erector pili muscles.
  • Lumen is filled with desquamated keratin sebum and hair shafts.
  • There is a sorrounding zone of compressed connective tissue.
  • Generally free of inflammation.

Epidermoid cyst

  • Same as dermoid cyst but skin appendages are absent.
  • Treatment is surgical enucleation. 
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